Bioequivalence of the 4-mg Oral Granules and Chewable Tablet Formulations of Montelukast
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چکیده
منابع مشابه
Bioequivalence of the 4-mg Oral Granules and Chewable Tablet Formulations of Montelukast
PURPOSE: The primary objective of the studies was to demonstrate bioequivalence between the oral granules formulation and chewable tablet of montelukast in the fasted state. Effect of food on the pharmacokinetics of the oral granules was also evaluated. METHODS: The Formulation Biocomparison Study (Study 1) and the Final Market Image Study (Study 2) each used an open-label, randomized, 3-period...
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Montelukast is an effective and well-tolerated treatment for the prophylaxis and chronic treatment of asthma, acute prevention of exercise-induced bronchoconstriction and symptomatic relief of seasonal allergic rhinitis and perennial allergic rhinitis. The aim of the study was to compare bioavailability, and characterise the pharmacokinetic profile and safety of Sandoz generic montelukast 4 mg ...
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Atenolol is a selective β1 receptor antagonist that is available as a racemic mixture. The objective of this study was to compare the pharmacokinetics and evaluate the bioequivalence of 50 mg atenolol test and reference formulations in 24 healthy Korean male volunteers.This study was a single-dose, randomized, open-label, 2 period crossover study. 24 healthy Korean male volunteers randomly rece...
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▼ Atenolol is a selective β 1 receptor antagonist that is available as a racemic mixture. The objective of this study was to compare the pharmacokinetics and evaluate the bioequivalence of 50 mg atenolol test and reference formulations in 24 healthy Korean male volunteers. This study was a single-dose, randomized, openlabel, 2 period crossover study. 24 healthy Korean male volunteers randomly r...
متن کاملComparative Pharmacokinetics and Bioequivalence of Two 50 mg Atenolol Tablet Formulations in Healthy Korean Male Volunteers
▼ Atenolol is a selective β 1 receptor antagonist that is available as a racemic mixture. The objective of this study was to compare the pharmacokinetics and evaluate the bioequivalence of 50 mg atenolol test and reference formulations in 24 healthy Korean male volunteers. This study was a single-dose, randomized, openlabel, 2 period crossover study. 24 healthy Korean male volunteers randomly r...
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ژورنال
عنوان ژورنال: Archives of Drug Information
سال: 2010
ISSN: 1753-5174,1753-5174
DOI: 10.1111/j.1753-5174.2010.00029.x